Cytoplasmic RNA Granules in Somatic Maintenance

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Multiple Poliovirus Proteins Repress Cytoplasmic RNA Granules

We have previously shown that poliovirus (PV) infection induces stress granule (SG) formation early in infection and then inhibits the formation of SG and disperses processing bodies (PBs) by the mid-phase of infection. Loss of SG was linked to cleavage of G3BP1 by viral 3C proteinase (3C(pro)), however dispersal of PBs was not strongly linked to cleavage of specific factors by viral proteinase...

متن کامل

RNA binding proteins, microRNAs, and Cytoplasmic RNA granules

Molecular Structure and Function, Research Institute, The Hospital for Sick Children, and 5 Department of Biochemistry & Laboratory Medicine, University of Toronto 6 s 7 8 9 10 Correspondence Address: 11 12 Program in Molecular Structure & Function 13 Research Institute, 14 The Hospital for Sick Children, 15 Atrium 3653; 555 University Avenue, 16 Toronto, Ontario, 17 M5G 1X8 18 Phone: 416-813-8...

متن کامل

RNA granules

Cytoplasmic RNA granules in germ cells (polar and germinal granules), somatic cells (stress granules and processing bodies), and neurons (neuronal granules) have emerged as important players in the posttranscriptional regulation of gene expression. RNA granules contain various ribosomal subunits, translation factors, decay enzymes, helicases, scaffold proteins, and RNA-binding proteins, and the...

متن کامل

A role for transportin in deposition of TTP to cytoplasmic RNA granules and mRNA decay

Importin-beta family members, which shuttle between the nucleus and the cytoplasm, are essential for nucleocytoplasmic transport of macromolecules. We attempted to explore whether importin-beta family proteins change their cellular localization in response to environmental change. In this report, we show that transportin (TRN) was minimally detected in cytoplasmic processing bodies (P-bodies) u...

متن کامل

RNA granules in germ cells.

"Germ granules" are cytoplasmic, nonmembrane-bound organelles unique to germline. Germ granules share components with the P bodies and stress granules of somatic cells, but also contain proteins and RNAs uniquely required for germ cell development. In this review, we focus on recent advances in our understanding of germ granule assembly, dynamics, and function. One hypothesis is that germ granu...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Gerontology

سال: 2018

ISSN: 0304-324X,1423-0003

DOI: 10.1159/000488759